Drug Information

Drug General Information
Drug ID
D0X5AY
Former ID
DNC007419
Drug Name
1-(4-methoxyphenyl)-3-(5-methylthiazol-2-yl)urea
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528805]
Formula
C12H13N3O2S
Canonical SMILES
CC1=CN=C(S1)NC(=O)NC2=CC=C(C=C2)OC
InChI
1S/C12H13N3O2S/c1-8-7-13-12(18-8)15-11(16)14-9-3-5-10(17-2)6-4-9/h3-7H,1-2H3,(H2,13,14,15,16)
InChIKey
OHPUNXDCCJNSEH-UHFFFAOYSA-N
PubChem Compound ID
771042
Target and Pathway
Target(s) mRNA of human 5-lipoxygenase Target Info Inhibitor [528805]
BioCyc Pathway Aspirin-triggered lipoxin biosynthesis
Resolvin D biosynthesis
Leukotriene biosynthesis
Lipoxin biosynthesis
Aspirin triggered resolvin D biosynthesis
Aspirin triggered resolvin E biosynthesis
KEGG Pathway Arachidonic acid metabolism
Metabolic pathways
Serotonergic synapse
Ovarian steroidogenesis
Toxoplasmosis
NetPath Pathway IL4 Signaling Pathway
PathWhiz Pathway Arachidonic Acid Metabolism
WikiPathways Arachidonic acid metabolism
Eicosanoid Synthesis
Selenium Micronutrient Network
References
Ref 528805J Med Chem. 2007 May 31;50(11):2640-6. Epub 2007 Apr 27.Identification of natural-product-derived inhibitors of 5-lipoxygenase activity by ligand-based virtual screening.
Ref 528805J Med Chem. 2007 May 31;50(11):2640-6. Epub 2007 Apr 27.Identification of natural-product-derived inhibitors of 5-lipoxygenase activity by ligand-based virtual screening.

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