TTD | Drug: D0X1QW

Drug General Information
Drug ID	D0X1QW
Former ID	DIB018063
Drug Name	(+)-AJ76
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[543336]
Formula	C15H23NO
InChI	InChI=1S/C15H23NO/c1-4-10-16-14-9-8-13-12(11(14)2)6-5-7-15(13)17-3/h5-7,11,14,16H,4,8-10H2,1-3H3/t11-,14+/m0/s1
InChIKey	YGHLYBIUVOLKCV-SMDDNHRTSA-N
PubChem Compound ID	122334
PubChem Substance ID	10240024, 11113640, 14798221, 26751835, 29302731, 47362778, 47586659, 47734099, 50065311, 57309654, 57340087, 75501132, 85788340, 103195613, 103973638, 104415576, 126678962, 129791697, 131342371, 135076599, 135610574, 135649912, 223683230, 226621554
Target and Pathway
Target(s)	D(3) dopamine receptor	Target Info	Antagonist	[530381]
KEGG Pathway	Neuroactive ligand-receptor interaction
KEGG Pathway	Dopaminergic synapse
Reactome	Dopamine receptors
Reactome	G alpha (i) signalling events
WikiPathways	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
	Nicotine Activity on Dopaminergic Neurons
	GPCRs, Other
References
Ref 543336	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 970).
Ref 530381	Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics. Nature. 1990 Sep 13;347(6289):146-51.

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Drug Information