Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0X1EY
|
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| Former ID |
DNC007313
|
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| Drug Name |
6-iodo-4'-hydroxyflavone
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [527855] | ||
| Formula |
C15H9IO3
|
||||
| Canonical SMILES |
C1=CC(=CC=C1C2=CC(=O)C3=C(O2)C=CC(=C3)I)O
|
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| InChI |
1S/C15H9IO3/c16-10-3-6-14-12(7-10)13(18)8-15(19-14)9-1-4-11(17)5-2-9/h1-8,17H
|
||||
| InChIKey |
IFAJNNUYROKKPW-UHFFFAOYSA-N
|
||||
| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Amyloid beta A4 protein | Target Info | Inhibitor | [527855] | |
| KEGG Pathway | Notch signaling pathway | ||||
| Alzheimer's disease | |||||
| Reactome | Nuclear signaling by ERBB4 | ||||
| Degradation of the extracellular matrix | |||||
| Regulated proteolysis of p75NTR | |||||
| NRIF signals cell death from the nucleus | |||||
| Activated NOTCH1 Transmits Signal to the Nucleus | |||||
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | |||||
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | |||||
| EPH-ephrin mediated repulsion of cells | |||||
| References | |||||
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