Drug Information

Drug General Information
Drug ID
D0W2PK
Former ID
DIB015682
Drug Name
Beloxepin
Synonyms
ADL-6906; Beloxepin (oral, pain); Beloxepin (oral, depression), Organon; Beloxepin (oral, pain), Adolor
Indication Depression [ICD9: 311; ICD10:F30-F39] Discontinued in Phase 1 [544856]
Company
Adolor Corp; Organon BioSciences
Canonical SMILES
O1c2c([C@]3([C@H](CN(CC3)C)c3c1c(ccc3)C)O)cccc2
CAS Number
CAS 135928-30-2
Target and Pathway
Target(s) 5-HT 2 receptor Target Info Modulator [550142]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Serotonergic synapse
Inflammatory mediator regulation of TRP channels
References
Ref 544856Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001334)
Ref 550142WO patent application no. 2009,1055,07, Beloxepin, its enantiomers, and analogs thereof for the treatment of pain.

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