Drug Information

Drug General Information
Drug ID
D0V9OL
Former ID
DIB000631
Drug Name
534U87
Synonyms
Anticonvulsant, Glaxo Wellcome; BW-534U87
Indication Epileptic seizures [ICD9: 345.9, 780.3; ICD10:G40, P90, R56] Discontinued in Phase 2 [546089]
Company
Burroughs Wellcome Inc
CAS Number
CAS 133563-45-8
Target and Pathway
Target(s) Sodium channel Target Info Modulator [525627]
KEGG Pathway Dopaminergic synapse
Reactome Interaction between L1 and Ankyrins
References
Ref 546089Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006296)
Ref 525627The anticonvulsant BW534U87 depresses epileptiform activity in rat hippocampal slices by an adenosine-dependent mechanism and through inhibition of voltage-gated Na+ channels. Br J Pharmacol. 1999 Nov;128(5):1011-20.

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