TTD | Drug: D0V8YH

Drug General Information
Drug ID	D0V8YH
Former ID	DIB020870
Drug Name	RvD1-ME
Synonyms	RvD1-methyl ester
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[540935]
Formula	C23H34O5
InChI	InChI=1S/C23H34O5/c1-3-4-10-15-20(24)16-11-7-5-6-8-12-17-21(25)22(26)18-13-9-14-19-23(27)28-2/h4-13,16-17,20-22,24-26H,3,14-15,18-19H2,1-2H3/b7-5-,8-6+,10-4-,13-9-,16-11+,17-12+/t20-,21+,22-/m0/s1
InChIKey	WUKVAFWBFGABJN-ZXQGQRHTSA-N
PubChem Compound ID	71519431
PubChem Substance ID	163511644, 178102196
Target and Pathway
Target(s)	FMLP-related receptor I	Target Info	Agonist	[531857]
Target(s)	GPR32	Target Info	Agonist	[531857]
Pathway Interaction Database	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
Reactome	G alpha (q) signalling events
Reactome	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 540935	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5555).
Ref 531857	Resolvin D1 receptor stereoselectivity and regulation of inflammation and proresolving microRNAs. Am J Pathol. 2012 May;180(5):2018-27.

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Drug Information