Drug Information

Drug General Information
Drug ID
D0V7HD
Former ID
DIB007860
Drug Name
BN-50726
Drug Type
Small molecular drug
Indication Nerve injury [ICD10:T14.4] Terminated [544993]
Company
Ipsen
Formula
C34H48ClN5O2S2
Canonical SMILES
c12c(C(=NCc3n1c(nn3)C)c1c(Cl)cccc1)c1c(s2)CN(S(=O)(=O)C<br />CCCCCCCCCCCCCCC)CC1
CAS Number
CAS 127279-06-5
PubChem Compound ID
164238
Target and Pathway
Target(s) Platelet-activating factor receptor Target Info Antagonist [526932]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Staphylococcus aureus infection
NetPath Pathway IL5 Signaling Pathway
Leptin Signaling Pathway
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (q) signalling events
Interferon gamma signaling
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Small Ligand GPCRs
Interferon gamma signaling
GPCR ligand binding
GPCR downstream signaling
References
Ref 544993Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001821)
Ref 526932Effects of the PAF antagonists BN50726 and BN50739 on arrhythmogenesis and extent of necrosis during myocardial ischaemia/reperfusion in rabbits. Br J Pharmacol. 1992 Nov;107(3):705-9.

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