Drug Information

Drug General Information
Drug ID
D0V4GT
Former ID
DIB001203
Drug Name
CMI-206
Synonyms
IDDB8444
Indication Inflammatory disease [ICD9: 140-229, 147, 173, 573.3, 710-719; ICD10:C11, C44, K75.9, M00-M25] Terminated [551572]
Company
CytoMed Inc
Canonical SMILES
C(=O)(Nc1c(c(cc([C@H]2O[C@H](c3cc(c(c(c3)OC)OC)OC)CC2)c<br />1)OC)OCCC)N(O)CCCC
Target and Pathway
Target(s) Arachidonate 5-lipoxygenase Target Info Modulator
Platelet-activating factor receptor Target Info Modulator
BioCyc Pathway Aspirin-triggered lipoxin biosynthesis
Resolvin D biosynthesis
Leukotriene biosynthesis
Lipoxin biosynthesis
Aspirin triggered resolvin D biosynthesis
Aspirin triggered resolvin E biosynthesis
KEGG Pathway Arachidonic acid metabolism
Metabolic pathways
Serotonergic synapse
Ovarian steroidogenesis
Toxoplasmosishsa04020:Calcium signaling pathway
Neuroactive ligand-receptor interaction
Staphylococcus aureus infection
NetPath Pathway IL4 Signaling PathwayNetPath_17:IL5 Signaling Pathway
Leptin Signaling Pathway
PathWhiz Pathway Arachidonic Acid Metabolism
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (q) signalling events
Interferon gamma signaling
WikiPathways Vitamin D Receptor Pathway
Arachidonic acid metabolism
Eicosanoid Synthesis
Selenium Micronutrient NetworkWP455:GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Small Ligand GPCRs
Interferon gamma signaling
GPCR ligand binding
GPCR downstream signaling
References
Ref 551572Cmi206: A potent dual platelet activating factor antagonist and 5-lipoxygenase inhibitor. Bioorganic & Medicinal Chemistry Letters. 03/1995; 5(6):643-648.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.