Drug Information

Drug General Information
Drug ID
D0V1EJ
Former ID
DNC012632
Drug Name
6-(2-Dipropylamino-ethyl)-biphenyl-2,3,4'-triol
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533481]
Formula
C20H27NO3
Canonical SMILES
CCCN(CCC)CCC1=C(C(=C(C=C1)O)O)C2=CC=C(C=C2)O
InChI
1S/C20H27NO3/c1-3-12-21(13-4-2)14-11-16-7-10-18(23)20(24)19(16)15-5-8-17(22)9-6-15/h5-10,22-24H,3-4,11-14H2,1-2H3
InChIKey
NTNWFRQRDDNMJY-UHFFFAOYSA-N
PubChem Compound ID
13678327
Target and Pathway
Target(s) Dopamine D1 receptor Target Info Inhibitor [533481]
KEGG Pathway Calcium signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Dopaminergic synapse
Parkinson's disease
Cocaine addiction
Amphetamine addiction
Morphine addiction
Alcoholism
PANTHER Pathway Dopamine receptor mediated signaling pathway
PathWhiz Pathway Dopamine Activation of Neurological Reward System
Reactome Dopamine receptors
G alpha (s) signalling events
WikiPathways Hypothetical Network for Drug Addiction
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Genes and (Common) Pathways Underlying Drug Addiction
GPCR ligand binding
GPCR downstream signaling
References
Ref 533481J Med Chem. 1986 Oct;29(10):1904-12.Synthesis and dopaminergic binding of 2-aryldopamine analogues: phenethylamines, 3-benzazepines, and 9-(aminomethyl)fluorenes.
Ref 533481J Med Chem. 1986 Oct;29(10):1904-12.Synthesis and dopaminergic binding of 2-aryldopamine analogues: phenethylamines, 3-benzazepines, and 9-(aminomethyl)fluorenes.

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