Drug Information

Drug General Information
Drug ID
D0UX4A
Former ID
DIB001674
Drug Name
HU-433
Synonyms
CB2 activator (osteoporosis); HU-433; CB2 activator (osteoporosis), Yissum
Indication Osteoporosis [ICD9: 733.0, V07.4; ICD10:M80-M81, Z79.890] Investigative [543878]
Company
Yissum Research Development Co
Canonical SMILES
c1(c(cc(cc1OC)C(CCCCCC)(C)C)OC)[C@@H]1C=C([C@H]2C(C)(C)<br />[C@@H]1C2)CO
Target and Pathway
Target(s) Cannabinoid receptor 2 Target Info Activator [543878]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 543878(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 57).
Ref 543878(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 57).

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