Drug Information

Drug General Information
Drug ID
D0U9NY
Former ID
DAP001436
Drug Name
Ultracet
Drug Type
Small molecular drug
Indication Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89] Approved [536242]
Therapeutic Class
Analgesics
Formula
C8H9NO2
Canonical SMILES
CC(=O)NC1=CC=C(C=C1)O
InChIKey
RZVAJINKPMORJF-UHFFFAOYSA-N
CAS Number
CAS 147630-09-9
PubChem Compound ID
1983
PubChem Substance ID
9023, 70391, 408305, 609360, 3131814, 4266416, 5199969, 7847284, 7890920, 7978634, 8149184, 8151363, 10321115, 10502811, 11112253, 11114188, 11335835, 11361074, 11362770, 11365332, 11367894, 11371386, 11373699, 11376056, 11462046, 11466896, 11468016, 11483746, 11486572, 11487901, 11490099, 11491955, 11493830, 11532417, 15321628, 17390068, 17436465, 22388563, 24714721, 24715004, 24890717, 24890930, 24891173, 24891200, 26512241, 26611588, 26679279, 26697092, 26747171, 26752236
Target and Pathway
Target(s) Sodium-dependent noradrenaline transporter Target Info Inhibitor [537457]
Sodium-dependent serotonin transporter Target Info Inhibitor [537457]
KEGG Pathway Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Adrenaline and noradrenaline biosynthesisP04373:5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathway
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways Monoamine Transport
NRF2 pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsWP727:Monoamine Transport
SIDS Susceptibility Pathways
Synaptic Vesicle Pathway
Serotonin Transporter Activity
References
Ref 536242The Diversion of Ultram, Ultracet, and generic tramadol HCL. J Addict Dis. 2006;25(2):53-8.
Ref 537457Augmentation effect of combination therapy of aripiprazole and antidepressants on forced swimming test in mice. Psychopharmacology (Berl). 2009 Jun 11.

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