Drug Information

Drug General Information
Drug ID
D0U9LT
Former ID
DIB016819
Drug Name
Y-39983
Synonyms
RKI-983; SNJ-1656; ROCK inhibitors, Mitsubishi Tanabe Pharma/Senju/Novartis; Rho-associated protein kinase inhibitors, Mitsubishi Tanabe Pharma/Senju/Novartis
Drug Type
Small molecular drug
Indication Glaucoma [ICD9: 365; ICD10:H40-H42] Phase 1/2 [522584]
Company
Mitsubishi Pharma Corp
Formula
C16H18Cl2N4O
Canonical SMILES
c1c(ccc(c1)C(=O)Nc1ccnc2c1cc[nH]2)[C@@H](C)N.Cl
PubChem Compound ID
20601328
Target and Pathway
Target(s) Rho associated protein kinase Target Info Modulator
References
Ref 522584ClinicalTrials.gov (NCT00846989) Efficacy, Tolerability and Safety of RKI983 (0.05% & 0.10%) vs Xalatan in Patients With POAG or Ocular Hypertension. U.S. National Institutes of Health.

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