TTD | Drug: D0U7SR

Drug General Information
Drug ID	D0U7SR
Former ID	DIB012346
Drug Name	RO-4998452
Synonyms	Type 2 diabetes therapeutic (oral), Roche
Indication	Type 2 diabetes [ICD9: 250; ICD10:E11]		Phase 2	[522503]
Company	F Hoffmann-La Roche Ltd
Target and Pathway
Target(s)	SLGT2	Target Info	Modulator
Reactome	Hexose transport
	Na+-dependent glucose transporters
	Inositol transporters
WikiPathways	NRF2 pathway
	Nuclear Receptors Meta-Pathway
	Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
References
Ref 522503	ClinicalTrials.gov (NCT00800176) A Dose-Finding Study of RO4998452 in Patients With Diabetes Mellitus. U.S. National Institutes of Health.

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Drug Information