Drug Information

Drug General Information
Drug ID
D0U6AL
Former ID
DIB013547
Drug Name
BI-L-357
Synonyms
BI-L-226
Drug Type
Small molecular drug
Indication Asthma [ICD10:J45] Terminated [545110]
Company
Boehringer Ingelheim Corp
Formula
C18H18O4S
Canonical SMILES
c1(c(cc(/C=C/c2sccc2)cc1C)C)OC(=O)CCC(=O)O
CAS Number
CAS 149539-02-6
PubChem Compound ID
6440014
Target and Pathway
Target(s) Arachidonate 5-lipoxygenase Target Info Inhibitor [534012]
BioCyc Pathway Aspirin-triggered lipoxin biosynthesis
Resolvin D biosynthesis
Leukotriene biosynthesis
Lipoxin biosynthesis
Aspirin triggered resolvin D biosynthesis
Aspirin triggered resolvin E biosynthesis
KEGG Pathway Arachidonic acid metabolism
Metabolic pathways
Serotonergic synapse
Ovarian steroidogenesis
Toxoplasmosis
NetPath Pathway IL4 Signaling Pathway
PathWhiz Pathway Arachidonic Acid Metabolism
WikiPathways Vitamin D Receptor Pathway
Arachidonic acid metabolism
Eicosanoid Synthesis
Selenium Micronutrient Network
References
Ref 545110Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002162)
Ref 534012A prodrug of a 2,6-disubstituted 4-(2-arylethenyl)phenol is a selective and orally active 5-lipoxygenase inhibitor. J Pharmacol Exp Ther. 1993 May;265(2):483-9.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.