Drug Information

Drug General Information
Drug ID
D0U4HM
Former ID
DIB021074
Drug Name
TPMPA
Synonyms
(1,2,5,6-tetrahydropyridine-4-yl)methylphosphinic acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [467666]
Formula
C6H12NO2P
InChI
InChI=1S/C6H12NO2P/c1-10(8,9)6-2-4-7-5-3-6/h2,7H,3-5H2,1H3,(H,8,9)
InChIKey
MFUKVPOVVKKLRQ-UHFFFAOYSA-N
PubChem Compound ID
5520
PubChem Substance ID
5658527, 8153396, 11111850, 17405818, 29224563, 50107214, 50107215, 53245706, 53778370, 85231243, 90341207, 92303397, 104309464, 121362034, 124750367, 124881537, 125815985, 131303010, 163218940, 163565218, 178101145
Target and Pathway
Target(s) GABAA receptor rho2 subunit Target Info Antagonist [543821]
GABAA receptor rho3 subunit Target Info Antagonist [543822]
GABAA receptor rho1 subunit Target Info Antagonist [543820]
References
Ref 467666(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4328).
Ref 543820(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 420).
Ref 543821(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 421).
Ref 543822(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 422).

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