TTD | Drug: D0U1DR

Drug General Information
Drug ID	D0U1DR
Former ID	DIB021200
Drug Name	VUF 4904
Synonyms	VUF-4904; VUF4904
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[538778]
Formula	C14H25N3
InChI	InChI=1S/C14H25N3/c1-3-7-13(8-4-1)16-10-6-2-5-9-14-11-15-12-17-14/h11-13,16H,1-10H2,(H,15,17)
InChIKey	XFSHNAXXKOSENG-UHFFFAOYSA-N
PubChem Compound ID	11492393
PubChem Substance ID	16594259, 42571257, 47434797, 47731178, 76204897, 103483724, 135651311, 136351929
Target and Pathway
Target(s)	Histamine H3 receptor	Target Info	Antagonist	[526200]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Histamine receptors
Reactome	G alpha (i) signalling events
WikiPathways	Monoamine Transport
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 538778	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1263).
Ref 526200	Constitutive activity of histamine h(3) receptors stably expressed in SK-N-MC cells: display of agonism and inverse agonism by H(3) antagonists. J Pharmacol Exp Ther. 2001 Dec;299(3):908-14.

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Drug Information