Drug Information

Drug General Information
Drug ID
D0TZ8C
Former ID
DNC004509
Drug Name
6-(2-Imidazol-1-yl-vinyl)-1H-quinolin-2-one
Drug Type
Small molecular drug
Indication Discovery agent Investigative [526726]
Formula
C14H11N3O
Canonical SMILES
C1=CC2=C(C=CC(=O)N2)C=C1C=CN3C=CN=C3
InChI
1S/C14H11N3O/c18-14-4-2-12-9-11(1-3-13(12)16-14)5-7-17-8-6-15-10-17/h1-10H,(H,16,18)/b7-5+
InChIKey
ULTZJAJIZBBKSG-FNORWQNLSA-N
PubChem Compound ID
14373279
Target and Pathway
Target(s) CGMP-inhibited 3',5'-cyclic phosphodiesterase A Target Info Inhibitor [526726]
KEGG Pathway Purine metabolism
cGMP-PKG signaling pathway
cAMP signaling pathway
Morphine addiction
Reactome cGMP effects
G alpha (s) signalling events
WikiPathways miR-targeted genes in muscle cell - TarBase
miR-targeted genes in lymphocytes - TarBase
References
Ref 526726J Med Chem. 1992 Feb 21;35(4):620-8.3,4-Dihydroquinolin-2(1H)-ones as combined inhibitors of thromboxane A2 synthase and cAMP phosphodiesterase.
Ref 526726J Med Chem. 1992 Feb 21;35(4):620-8.3,4-Dihydroquinolin-2(1H)-ones as combined inhibitors of thromboxane A2 synthase and cAMP phosphodiesterase.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.