Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0TN0D
|
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| Former ID |
DNC008747
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| Drug Name |
METAZOCINE
|
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [529816] | ||
| Formula |
C15H21NO
|
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| Canonical SMILES |
CC1C2CC3=C(C1(CCN2C)C)C=C(C=C3)O
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| InChI |
1S/C15H21NO/c1-10-14-8-11-4-5-12(17)9-13(11)15(10,2)6-7-16(14)3/h4-5,9-10,14,17H,6-8H2,1-3H3
|
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| InChIKey |
YGSVZRIZCHZUHB-UHFFFAOYSA-N
|
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| CAS Number |
CAS 3734-52-9
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Delta-type opioid receptor | Target Info | Inhibitor | [529816] | |
| Kappa-type opioid receptor | Target Info | Inhibitor | [529816] | ||
| Mu-type opioid receptor | Target Info | Inhibitor | [533571] | ||
| NetPath Pathway | TCR Signaling Pathway | ||||
| PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||||
| Enkephalin release | |||||
| Opioid proenkephalin pathway | |||||
| Opioid proopiomelanocortin pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||||
| Opioid prodynorphin pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||||
| Pathway Interaction Database | IL4-mediated signaling events | ||||
| References | |||||
| Ref 529816 | Bioorg Med Chem Lett. 2009 Jan 1;19(1):203-8. Epub 2008 Nov 7.Syntheses and opioid receptor binding properties of carboxamido-substituted opioids. | ||||
| Ref 533571 | J Med Chem. 1982 Dec;25(12):1423-7.Synthesis and biological evaluation of a metazocine-containing enkephalinamide. Evidence for nonidentical roles of the tyramine moiety in opiates and opioid peptides. | ||||
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