Drug Information

Drug General Information
Drug ID
D0T8LY
Former ID
DNC004080
Drug Name
PYRIDINE
Drug Type
Small molecular drug
Indication Discovery agent Phase 4 [524763]
Formula
C5H5N
Canonical SMILES
CN1CCCC1C2=CN=CC=C2.C(C(C(=O)O)O)(C(=O)O)O
InChI
1S/C10H14N2.C4H6O6/c1-12-7-3-5-10(12)9-4-2-6-11-8-9;5-1(3(7)8)2(6)4(9)10/h2,4,6,8,10H,3,5,7H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)
InChIKey
QLDPCHZQQIASHX-UHFFFAOYSA-N
PubChem Compound ID
1049
Target and Pathway
Target(s) Thromboxane-A synthase Target Info Inhibitor [533575]
BioCyc Pathway C20 prostanoid biosynthesis
KEGG Pathway Arachidonic acid metabolism
Metabolic pathways
Platelet activation
PathWhiz Pathway Arachidonic Acid Metabolism
WikiPathways Prostaglandin Synthesis and Regulation
Arachidonic acid metabolism
Phase 1 - Functionalization of compounds
Eicosanoid Synthesis
References
Ref 524763ClinicalTrials.gov (NCT02143167) Resistance Training and Amino Pyridine in Multiple Sclerosis. U.S. National Institutes of Health.
Ref 533575J Med Chem. 1981 Oct;24(10):1149-55.Highly selective inhibitors of thromboxane synthetase. 2. Pyridine derivatives.

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