Drug Information

Drug General Information
Drug ID
D0T1MK
Former ID
DIB020281
Drug Name
LY382884
Synonyms
LY-382884; LY 382884
Drug Type
Small molecular drug
Indication Discovery agent Investigative [467582]
Formula
C18H23NO4
InChI
InChI=1S/C18H23NO4/c20-17(21)13-4-1-11(2-5-13)7-12-3-6-14-10-19-16(18(22)23)9-15(14)8-12/h1-2,4-5,12,14-16,19H,3,6-10H2,(H,20,21)(H,22,23)/t12-,14+,15-,16+/m1/s1
InChIKey
YVMADKYPKNLVGU-BVUBDWEXSA-N
PubChem Compound ID
656723
PubChem Substance ID
586319, 9268114, 14776868, 50076892, 51702495, 103180150, 104053850, 113528141, 134222949, 136038500, 142251027, 178101064, 223442395, 227986950
Target and Pathway
Target(s) Glutamate receptor, ionotropic kainate 1 Target Info Antagonist [543831]
KEGG Pathway Neuroactive ligand-receptor interaction
Glutamatergic synapse
PANTHER Pathway Huntington disease
Ionotropic glutamate receptor pathway
Metabotropic glutamate receptor group III pathway
Metabotropic glutamate receptor group I pathway
WikiPathways Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
References
Ref 467582(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4247).
Ref 543831(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 450).

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