Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0SZ3B
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| Former ID |
DIB005668
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| Drug Name |
ER-34122
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| Drug Type |
Small molecular drug
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| Company |
Eisai Co Ltd
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| Formula |
C27H26ClN3O5
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| Canonical SMILES |
c1(nn(c(c1)c1ccc(cc1)OC)c1ccc(cc1)OC)C(c1cc(C(=O)N)c(cc<br />1)Cl)(OC)OC
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| CAS Number |
CAS 179325-62-3
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Arachidonate 5-lipoxygenase | Target Info | Modulator | [526240], [534759] | |
| NetPath Pathway | IL4 Signaling Pathway | ||||
| PathWhiz Pathway | Arachidonic Acid Metabolism | ||||
| References | |||||
| Ref 526240 | Improvement of dissolution and oral absorption of ER-34122, a poorly water-soluble dual 5-lipoxygenase/cyclooxygenase inhibitor with anti-inflammatory activity by preparing solid dispersion. J Pharm Sci. 2002 Jan;91(1):258-66. | ||||
| Ref 534759 | ER-34122, a novel dual 5-lipoxygenase/cyclooxygenase inhibitor with potent anti-inflammatory activity in an arachidonic acid-induced ear inflammation model. Inflamm Res. 1998 Oct;47(10):375-83. | ||||
| Ref 526240 | Improvement of dissolution and oral absorption of ER-34122, a poorly water-soluble dual 5-lipoxygenase/cyclooxygenase inhibitor with anti-inflammatory activity by preparing solid dispersion. J Pharm Sci. 2002 Jan;91(1):258-66. | ||||
| Ref 534759 | ER-34122, a novel dual 5-lipoxygenase/cyclooxygenase inhibitor with potent anti-inflammatory activity in an arachidonic acid-induced ear inflammation model. Inflamm Res. 1998 Oct;47(10):375-83. | ||||
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