Drug Information

Drug General Information
Drug ID
D0SE4D
Former ID
DIB003188
Drug Name
Org-20599
Synonyms
Org-20549
Drug Type
Small molecular drug
Indication Anesthesia [ICD9: 338; ICD10:R20.0] Terminated [545545]
Company
Organon BioSciences
Formula
C25H40ClNO3
Canonical SMILES
[C@@]12([C@@H]3[C@H]([C@H]4[C@@]([C@H](CC4)C(=O)CCl)(CC<br />3)C)CC[C@H]2C[C@@H]([C@H](C1)N1CCOCC1)O)C.S(=O)(=O)(O)C
CAS Number
CAS 187652-71-7
PubChem Compound ID
656747
Target and Pathway
Target(s) GABA A receptor delta subunit Target Info Modulator [534312]
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addiction
References
Ref 545545Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003651)
Ref 534312The anaesthetic action and modulation of GABAA receptor activity by the novel water-soluble aminosteroid Org 20599. Neuropharmacology. 1996;35(9-10):1209-22.

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