Drug Information

Drug General Information
Drug ID
D0S8HE
Former ID
DIB020455
Drug Name
MSOPPE
Synonyms
alpha-methylserine-O-phosphate monophenyl ester
Drug Type
Small molecular drug
Indication Discovery agent Investigative [538917]
Formula
C10H14NO6P
InChI
InChI=1S/C10H14NO6P/c1-10(11,9(12)13)7-16-18(14,15)17-8-5-3-2-4-6-8/h2-6H,7,11H2,1H3,(H,12,13)(H,14,15)
InChIKey
GBCGDIQJCHNFKA-UHFFFAOYSA-N
PubChem Compound ID
5311463
PubChem Substance ID
7980689, 11056526, 15393354, 26756627, 39341136, 51656811, 57359494, 85209995, 114156166, 135650669, 237693841, 242401772
Target and Pathway
Target(s) Metabotropic glutamate receptor 7 Target Info Antagonist [525945]
KEGG Pathway Neuroactive ligand-receptor interaction
Glutamatergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Metabotropic glutamate receptor group III pathway
Reactome G alpha (i) signalling events
Class C/3 (Metabotropic glutamate/pheromone receptors)
WikiPathways GPCRs, Class C Metabotropic glutamate, pheromone
GPCR ligand binding
GPCR downstream signaling
References
Ref 538917(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1440).
Ref 525945Binding of [3H](2S,1'S,2'S)-2-(9-xanthylmethyl)-2-(2'-carboxycyclopropyl) glycine ([3H]LY341495) to cell membranes expressing recombinant human group III metabotropic glutamate receptor subtypes. Naunyn Schmiedebergs Arch Pharmacol. 2000 Dec;362(6):546-54.

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