Drug Information

Drug General Information
Drug ID
D0S7VN
Former ID
DIB009253
Drug Name
MRL-953
Synonyms
SDZ-MRL-953
Indication Immune disorder [ICD10:D80-D89] Terminated [545071]
Company
Novartis AG
Canonical SMILES
[C@H]1([C@@H]([C@H]([C@@H]([C@H](O1)CO)OC(=O)C[C@H](O)C<br />CCCCCCCCCC)OC(=O)C[C@H](O)CCCCCCCCCCC)NC(=O)C[C@H](O)CC<br />CCCCCCCCC)OP(=O)(O)O
CAS Number
CAS 123136-61-8
Target and Pathway
Target(s) Interleukin-1 receptor, type II Target Info Agonist [534068]
KEGG Pathway MAPK signaling pathway
Cytokine-cytokine receptor interaction
Hematopoietic cell lineage
Amoebiasis
HTLV-I infection
Transcriptional misregulation in cancer
NetPath Pathway IL1 Signaling Pathway
TNFalpha Signaling Pathway
Pathway Interaction Database IL1-mediated signaling events
Reactome Interleukin-1 signaling
WikiPathways MAPK Signaling Pathway
Interleukin-1 signaling
Apoptosis Modulation and Signaling
References
Ref 545071Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002036)
Ref 534068SDZ MRL 953, a lipid A analog as selective cytokine inducer. Prog Clin Biol Res. 1995;392:549-65.

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