Drug Information

Drug General Information
Drug ID
D0S5BV
Former ID
DNCL001605
Drug Name
ABT-652
Indication Diabetic neuropathy; Musculoskeletal pain [ICD9: 250, 250.6, 356.0, 356.8, 338, 780; ICD10:E11.40, R52, G89] Phase 2 [523180]
Company
Abbott Laboratories
Target and Pathway
Target(s) Histamine H3 receptor Target Info Modulator [549101]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Histamine receptors
G alpha (i) signalling events
WikiPathways Monoamine Transport
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 523180ClinicalTrials.gov (NCT01207115) A Study of ABT-652 in Adults With Osteoarthritis Pain of the Knee. U.S. National Institutes of Health.
Ref 549101Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800032225)

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