Drug Information

Drug General Information
Drug ID
D0S4FV
Former ID
DIB018087
Drug Name
(R)-N-oleoyltyrosinol
Drug Type
Small molecular drug
Indication Discovery agent Investigative [541058]
Formula
C27H45NO3
InChI
InChI=1S/C27H45NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-27(31)28-25(23-29)22-24-18-20-26(30)21-19-24/h9-10,18-21,25,29-30H,2-8,11-17,22-23H2,1H3,(H,28,31)/b10-9+/t25-/m1/s1
InChIKey
ICDMLAQPOAVWNH-YHZGQTRVSA-N
PubChem Compound ID
73755147
PubChem Substance ID
178102346
Target and Pathway
Target(s) Glucose-dependent insulinotropic receptor Target Info Agonist [530508]
KEGG Pathway cAMP signaling pathway
Insulin secretion
WikiPathways Incretin Synthesis, Secretion, and Inactivation
References
Ref 541058(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5720).
Ref 530508N-oleoyldopamine enhances glucose homeostasis through the activation of GPR119. Mol Endocrinol. 2010 Jan;24(1):161-70.

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