Drug Information

Drug General Information
Drug ID
D0S1RT
Former ID
DIB010687
Drug Name
UK-290795
Indication Urinary incontinence [ICD9: 788.3; ICD10:N39.3, N39.4, R32] Terminated [547543]
Company
Pfizer Inc
Canonical SMILES
[C@]1(c2cc(c(cc2)Cl)Cl)(CN(CC2CCC(CC2)(F)F)C(=O)CC1)CCN<br />1CC(C1)N1CCC(CC1)F
Target and Pathway
Target(s) NK-2 receptor Target Info Antagonist [547544]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Reactome G alpha (q) signalling events
WikiPathways Gastrin-CREB signalling pathway via PKC and MAPK
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 547543Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800017162)
Ref 547544Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800017162)

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