Drug Information

Drug General Information
Drug ID
D0S0OV
Former ID
DNC004513
Drug Name
1-(7-Methoxy-2-phenyl-chroman-4-yl)-1H-imidazole
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527222]
Formula
C19H18N2O2
Canonical SMILES
COC1=CC2=C(C=C1)C(CC(O2)C3=CC=CC=C3)N4C=CN=C4
InChI
1S/C19H18N2O2/c1-22-15-7-8-16-17(21-10-9-20-13-21)12-18(23-19(16)11-15)14-5-3-2-4-6-14/h2-11,13,17-18H,12H2,1H3
InChIKey
JEQHTTKNYWNYDK-UHFFFAOYSA-N
PubChem Compound ID
10267149
Target and Pathway
Target(s) Cytochrome P450 19 Target Info Inhibitor [527222]
BioCyc Pathway Superpathway of steroid hormone biosynthesis
Estradiol biosynthesis II
Estradiol biosynthesis I
KEGG Pathway Steroid hormone biosynthesis
Metabolic pathways
Ovarian steroidogenesis
NetPath Pathway FSH Signaling Pathway
PANTHER Pathway Androgen/estrogene/progesterone biosynthesis
PathWhiz Pathway Androgen and Estrogen Metabolism
Reactome Endogenous sterols
WikiPathways Metapathway biotransformation
Tryptophan metabolism
Oxidation by Cytochrome P450
Ovarian Infertility Genes
Metabolism of steroid hormones and vitamin D
FSH signaling pathway
Integrated Breast Cancer Pathway
Phase 1 - Functionalization of compounds
References
Ref 527222Bioorg Med Chem Lett. 2004 Oct 18;14(20):5215-8.Synthesis and evaluation of 4-triazolylflavans as new aromatase inhibitors.
Ref 527222Bioorg Med Chem Lett. 2004 Oct 18;14(20):5215-8.Synthesis and evaluation of 4-triazolylflavans as new aromatase inhibitors.

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