Drug Information

Drug General Information
Drug ID
D0S0DT
Former ID
DIB019071
Drug Name
CAY10583
Synonyms
compound A [PMID:15866883]; CAY 10583; CAY-10583
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527543]
Formula
C25H25NO3
InChI
InChI=1S/C25H25NO3/c1-2-3-13-24(27)26(21-9-5-4-6-10-21)18-19-14-16-20(17-15-19)22-11-7-8-12-23(22)25(28)29/h4-12,14-17H,2-3,13,18H2,1H3,(H,28,29)
InChIKey
IUJTVDNJFPZYBL-UHFFFAOYSA-N
PubChem Compound ID
51529932
PubChem Substance ID
125334042, 141622657, 163501864, 178102782, 229171276, 243577022
Target and Pathway
Target(s) Leukotriene B4 receptor 2 Target Info Agonist [527543]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
PANTHER Pathway Inflammation mediated by chemokine and cytokine signaling pathway
Reactome Leukotriene receptors
G alpha (q) signalling events
WikiPathways Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 527543Characterization of a mouse second leukotriene B4 receptor, mBLT2: BLT2-dependent ERK activation and cell migration of primary mouse keratinocytes. J Biol Chem. 2005 Jul 1;280(26):24816-23. Epub 2005 May 2.
Ref 527543Characterization of a mouse second leukotriene B4 receptor, mBLT2: BLT2-dependent ERK activation and cell migration of primary mouse keratinocytes. J Biol Chem. 2005 Jul 1;280(26):24816-23. Epub 2005 May 2.

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