Drug Information

Drug General Information
Drug ID
D0RF4L
Former ID
DIB018656
Drug Name
5-methoxy-luzindole
Synonyms
5-methoxyluzindole
Drug Type
Small molecular drug
Indication Discovery agent Investigative [538842]
Formula
C20H22N2O2
InChI
InChI=1S/C20H22N2O2/c1-14(23)21-11-10-17-18-13-16(24-2)8-9-19(18)22-20(17)12-15-6-4-3-5-7-15/h3-9,13,22H,10-12H2,1-2H3,(H,21,23)
InChIKey
MUQOTEHRXIKHKR-UHFFFAOYSA-N
PubChem Compound ID
129776
PubChem Substance ID
10242428, 14850592, 29308527, 57343152, 79588665, 85208926, 103357287, 104371246, 128650265, 135085770, 135649838, 136351166, 142374851, 234722156
Target and Pathway
Target(s) Melatonin receptor Target Info Agonist [534353]
KEGG Pathway Neuroactive ligand-receptor interaction
Circadian entrainment
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 538842(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1364).
Ref 534353Melatonin receptor antagonists that differentiate between the human Mel1a and Mel1b recombinant subtypes are used to assess the pharmacological profile of the rabbit retina ML1 presynaptic heteroreceptor. Naunyn Schmiedebergs Arch Pharmacol. 1997 Mar;355(3):365-75.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.