Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0R5XK
|
||||
| Former ID |
DNC012014
|
||||
| Drug Name |
ONO-1714
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | Septic shock [ICD9: 785.52; ICD10:A41.9] | Discontinued in Phase 1 | [547187] | ||
| Formula |
C7H11ClN2
|
||||
| Canonical SMILES |
CC1CC(=NC2C1C2Cl)N
|
||||
| InChI |
1S/C7H11ClN2/c1-3-2-4(9)10-7-5(3)6(7)8/h3,5-7H,2H2,1H3,(H2,9,10)/t3-,5-,6+,7-/m0/s1
|
||||
| InChIKey |
SEVICIFJHBFRBO-OIADKPKDSA-N
|
||||
| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Nitric oxide synthase, inducible | Target Info | Modulator | ||
| BioCyc Pathway | Citrulline-nitric oxide cycle | ||||
| KEGG Pathway | Arginine biosynthesis | ||||
| Arginine and proline metabolism | |||||
| Metabolic pathways | |||||
| Calcium signaling pathway | |||||
| HIF-1 signaling pathway | |||||
| Peroxisome | |||||
| Salmonella infection | |||||
| Pertussis | |||||
| Leishmaniasis | |||||
| Chagas disease (American trypanosomiasis) | |||||
| Toxoplasmosis | |||||
| Amoebiasis | |||||
| Tuberculosis | |||||
| Pathways in cancer | |||||
| Small cell lung cancer | |||||
| NetPath Pathway | IL1 Signaling Pathway | ||||
| IL2 Signaling Pathway | |||||
| References | |||||
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