Drug Information

Drug General Information
Drug ID
D0R2SK
Former ID
DIB007558
Drug Name
Erteberel
Synonyms
LY-500307; SERBA-1; ER beta agonist (BPH), Lilly; Lead estrogen receptor beta agonists (benign prostatic hyperplasia),Eli Lilly
Drug Type
Small molecular drug
Indication Prostate hyperplasia [ICD10:N40] Phase 2 [524322]
Company
Eli Lilly & Co
Formula
C18H18O3
Canonical SMILES
[C@H]12[C@H](c3c(O[C@H]1c1ccc(cc1)O)ccc(c3)O)CCC2
CAS Number
CAS 533884-09-2
PubChem Compound ID
10286159
Target and Pathway
Target(s) Estrogen receptor beta Target Info Agonist [549074]
KEGG Pathway Estrogen signaling pathway
Prolactin signaling pathway
Pathway Interaction Database Plasma membrane estrogen receptor signaling
Validated nuclear estrogen receptor beta network
Validated nuclear estrogen receptor alpha network
Reactome Nuclear Receptor transcription pathway
WikiPathways SIDS Susceptibility Pathways
Ovarian Infertility Genes
Integrated Pancreatic Cancer Pathway
Nuclear Receptors
References
Ref 524322ClinicalTrials.gov (NCT01874756) The Efficacy and Safety of a Selective Estrogen Receptor Beta Agonist (LY500307) for Negative Symptoms and Cognitive Impairment Associated With Schizophrenia. U.S. National Institutes of Health.
Ref 549074Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800031986)

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