Drug Information

Drug General Information
Drug ID
D0R2KL
Former ID
DIB020161
Drug Name
L-644,698
Synonyms
L644698; L-644698
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539179]
Formula
C21H31NO4S
InChI
InChI=1S/C21H31NO4S/c1-2-3-4-7-18(23)13-14-22-19(24)15-27-20(22)8-5-6-16-9-11-17(12-10-16)21(25)26/h9-12,18,20,23H,2-8,13-15H2,1H3,(H,25,26)
InChIKey
NDAXAJCKSWCWQI-UHFFFAOYSA-N
PubChem Compound ID
9908595
PubChem Substance ID
14878722, 24189522, 45980258, 76885268, 85209130, 103341960, 128684775, 135650477, 224822390, 236043151
Target and Pathway
Target(s) Prostaglandin D2 receptor Target Info Agonist [525559]
KEGG Pathway Neuroactive ligand-receptor interaction
Pathway Interaction Database Thromboxane A2 receptor signaling
PathWhiz Pathway Intracellular Signalling Through PGD2 receptor and Prostaglandin D2
Reactome Prostanoid ligand receptors
G alpha (s) signalling events
WikiPathways Prostaglandin Synthesis and Regulation
GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 539179(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1879).
Ref 525559A novel biological role for prostaglandin D2 is suggested by distribution studies of the rat DP prostanoid receptor. Eur J Pharmacol. 1999 Jul 14;377(1):101-15.

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