Drug Information

Drug General Information
Drug ID
D0R2ES
Former ID
DNC011955
Drug Name
2-Phenyl-5,6-dihydro-pyrazolo[1,5-c]quinazoline
Drug Type
Small molecular drug
Indication Discovery agent Investigative [534157]
Formula
C16H13N3
Canonical SMILES
C1N=C2C=CC=CC2=C3N1NC(=C3)C4=CC=CC=C4
InChI
1S/C16H13N3/c1-2-6-12(7-3-1)15-10-16-13-8-4-5-9-14(13)17-11-19(16)18-15/h1-10,18H,11H2
InChIKey
PJUDEWJNGXVAML-UHFFFAOYSA-N
PubChem Compound ID
10681942
Target and Pathway
Target(s) Gamma-aminobutyric acid receptor Target Info Inhibitor [534157]
Gamma-aminobutyric acid receptor subunit alpha-1 Target Info Inhibitor [534157]
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addiction
Reactome Ligand-gated ion channel transport
GABA A receptor activation
WikiPathways SIDS Susceptibility Pathways
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transport
References
Ref 534157J Med Chem. 1996 Jul 19;39(15):2915-21.Synthesis and binding activity of some pyrazolo[1,5-c]quinazolines as tools to verify an optional binding site of a benzodiazepine receptor ligand.
Ref 534157J Med Chem. 1996 Jul 19;39(15):2915-21.Synthesis and binding activity of some pyrazolo[1,5-c]quinazolines as tools to verify an optional binding site of a benzodiazepine receptor ligand.

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