Drug Information

Drug General Information
Drug ID
D0R1AE
Former ID
DNC007690
Drug Name
Methyl 2-(naphthalen-2-yl)benzoate
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528794]
Formula
C18H14O2
Canonical SMILES
COC(=O)C1=CC=CC=C1C2=CC3=CC=CC=C3C=C2
InChI
1S/C18H14O2/c1-20-18(19)17-9-5-4-8-16(17)15-11-10-13-6-2-3-7-14(13)12-15/h2-12H,1H3
InChIKey
SKSUKRWKVAZHJI-UHFFFAOYSA-N
PubChem Compound ID
44332186
Target and Pathway
Target(s) Sodium-dependent dopamine transporter Target Info Inhibitor [528794]
KEGG Pathway Dopaminergic synapse
Parkinson's disease
Cocaine addiction
Amphetamine addiction
Alcoholism
PANTHER Pathway Adrenaline and noradrenaline biosynthesis
Parkinson disease
Dopamine receptor mediated signaling pathway
Pathway Interaction Database Alpha-synuclein signaling
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways Monoamine Transport
NRF2 pathway
Dopaminergic Neurogenesis
Parkinsons Disease Pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
Neurotransmitter Clearance In The Synaptic Cleft
References
Ref 528794Bioorg Med Chem. 2007 Jun 15;15(12):4159-74. Epub 2007 Mar 30.Synthesis, inhibition and binding of simple non-nitrogen inhibitors of monoamine transporters.
Ref 528794Bioorg Med Chem. 2007 Jun 15;15(12):4159-74. Epub 2007 Mar 30.Synthesis, inhibition and binding of simple non-nitrogen inhibitors of monoamine transporters.

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