Drug Information

Drug General Information
Drug ID
D0QG6A
Former ID
DNC001020
Drug Name
NIP-142
Drug Type
Small molecular drug
Indication Atrial fibrillation [ICD9: 272, 427.31; ICD10:E78, I48] Investigative [539537]
Company
Aventis
Formula
C23H27N3O6
InChI
InChI=1S/C23H27N3O6/c1-23(2)22(28)21(24-14-6-7-14)16-11-17(18(26(29)30)12-19(16)32-23)25-20(27)10-13-4-8-15(31-3)9-5-13/h4-5,8-9,11-12,14,21-22,24,28H,6-7,10H2,1-3H3,(H,25,27)/t21-,22+/m0/s1
InChIKey
HWADWMAQVCHLHJ-FCHUYYIVSA-N
CAS Number
CAS 203002-75-9
PubChem Compound ID
9980734
PubChem Substance ID
14958728, 24243776, 44032074, 80391139, 124963092, 135650721, 142572642, 143344327, 163366989, 247272594
Target and Pathway
Target(s) Potassium voltage-gated channel subfamily A member 5 Target Info Blocker [536095]
PathWhiz Pathway Muscle/Heart Contraction
Reactome Voltage gated Potassium channels
WikiPathways Potassium Channels
References
Ref 539537(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2408).
Ref 536095New antiarrhythmic agents for atrial fibrillation and atrial flutter. Expert Opin Emerg Drugs. 2005 May;10(2):311-22.

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