Drug Information

Drug General Information
Drug ID
D0Q9WO
Former ID
DAP001250
Drug Name
Cinolazepam
Synonyms
Cinolazepamum; Gerodorm; Cinolazepam [INN]; OX 373; Cinolazepam (INN); Cinolazepamum [INN-Latin]; Gerodorm (TN); OX-373;1-(2-cyanoethyl)-7-chloro-3-hydroxy-5-(2'-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 3-[7-chloro-5-(2-fluorophenyl)-3-hydroxy-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-1-yl]propanenitrile; 3-[7-chloro-5-(2-fluorophenyl)-3-hydroxy-2-oxo-3H-1,4-benzodiazepin-1-yl]propanenitrile; 7-Chloro-5-(o-fluorophenyl)-2,3-dihydro-3-hydroxy-2-oxo-1H-1,4-benzodiazepine-1-propionitrile; 7-chloro-5-(2-fluorophenyl)-2,3-dihydro-3-hydroxy-2-oxo-1H-1,4-benzodiazepine-1-propanenitrile
Drug Type
Small molecular drug
Indication Muscle relaxant [ICD10:N39.3, N39.4, R32] Approved [550708]
Therapeutic Class
Anticonvulsants
Formula
C18H13ClFN3O2
Canonical SMILES
C1=CC=C(C(=C1)C2=NC(C(=O)N(C3=C2C=C(C=C3)Cl)CCC#N)O)F
InChI
1S/C18H13ClFN3O2/c19-11-6-7-15-13(10-11)16(12-4-1-2-5-14(12)20)22-17(24)18(25)23(15)9-3-8-21/h1-2,4-7,10,17,24H,3,9H2
InChIKey
XAXMYHMKTCNRRZ-UHFFFAOYSA-N
CAS Number
CAS 75696-02-5
PubChem Compound ID
3033621
PubChem Substance ID
10047721, 12013302, 15497116, 36077499, 46508803, 49884064, 50734456, 51091665, 57352746, 93581448, 109714088, 111634607, 117617476, 129662608, 134338487, 135012013, 137156383, 160676529, 160964832, 179151089, 184533780, 226741902, 241135759
SuperDrug ATC ID
N05CD13
SuperDrug CAS ID
cas=075696025
Target and Pathway
Target(s) Peripheral-type benzodiazepine receptor Target Info Binder [537708]
KEGG Pathway Neuroactive ligand-receptor interaction
HTLV-I infection
References
Ref 550708Drug information of Cinolazepam, 2008. eduDrugs.
Ref 537708Short-term sleep laboratory studies with cinolazepam in situational insomnia induced by traffic noise. Int J Clin Pharmacol Res. 1987;7(5):407-18.

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