Drug Information

Drug General Information
Drug ID
D0Q8YN
Former ID
DIB007268
Drug Name
Sch-40338
Drug Type
Small molecular drug
Indication Allergy [ICD9: 995.3; ICD10:T78.4] Terminated [529095], [539163]
Company
Schering-Plough Corp
Formula
C20H22ClN3O
InChI
InChI=1S/C20H22ClN3O/c1-14(25)23-9-11-24(12-10-23)20-18-7-6-17(21)13-16(18)5-4-15-3-2-8-22-19(15)20/h2-3,6-8,13,20H,4-5,9-12H2,1H3
InChIKey
AIESXMXVDNOKQF-UHFFFAOYSA-N
CAS Number
CAS 117796-62-0
PubChem Compound ID
9950564
PubChem Substance ID
14925700, 24221006, 46047179, 77391535, 103342007, 103966637, 127410352, 135651027, 224941802, 234341019
Target and Pathway
Target(s) Platelet-activating factor receptor Target Info Modulator
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Staphylococcus aureus infection
NetPath Pathway IL5 Signaling Pathway
Leptin Signaling Pathway
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (q) signalling events
Interferon gamma signaling
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Small Ligand GPCRs
Interferon gamma signaling
GPCR ligand binding
GPCR downstream signaling
References
Ref 529095Sch 37370: a new drug combining antagonism of platelet-activating factor (PAF) with antagonism of histamine. Agents Actions Suppl. 1991;34:313-21.
Ref 539163(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1854).

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