Drug Information

Drug General Information
Drug ID
D0Q8MI
Former ID
DIB013200
Drug Name
Lintopride
Synonyms
SL-920075
Drug Type
Small molecular drug
Indication Nausea [ICD10:R11] Phase 2 [534100]
Company
Synthelabo
Formula
C14H19ClN4O2
Canonical SMILES
c1(C(=O)NCC2=NCCN2CC)c(cc(c(c1)Cl)N)OC
CAS Number
CAS 107429-63-0
PubChem Compound ID
65900
Target and Pathway
Target(s) 5-hydroxytryptamine 4 receptor Target Info Modulator [534100]
5-HT 3 receptor Target Info Modulator [534100]
KEGG Pathway Calcium signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
5HT4 type receptor mediated signaling pathway
PathWhiz Pathway Excitatory Neural Signalling Through 5-HTR 4 and Serotonin
Reactome Serotonin receptors
G alpha (s) signalling events
WikiPathways Serotonin Receptor 4/6/7 and NR3C Signaling
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 534100The effects of lintopride, a 5HT-4 antagonist, on oesophageal motility. Aliment Pharmacol Ther. 1995 Oct;9(5):563-9.
Ref 534100The effects of lintopride, a 5HT-4 antagonist, on oesophageal motility. Aliment Pharmacol Ther. 1995 Oct;9(5):563-9.

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