TTD | Drug: D0Q6TU

Drug General Information
Drug ID	D0Q6TU
Former ID	DIB019968
Drug Name	GT2394
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[538776]
Formula	C14H21N3O2
InChI	InChI=1S/C14H21N3O2/c18-14(19-8-10-4-2-1-3-5-10)17-12-6-11(12)13-7-15-9-16-13/h7,9-12H,1-6,8H2,(H,15,16)(H,17,18)/t11-,12-/m1/s1
InChIKey	SLQAVEDMASVHTL-VXGBXAGGSA-N
PubChem Compound ID	9860053
PubChem Substance ID	14823836, 14823837, 45282343, 50076815, 74558682, 135650325, 140127572, 142987937, 226948254, 242923065
Target and Pathway
Target(s)	Histamine H3 receptor	Target Info	Antagonist	[526445]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Histamine receptors
Reactome	G alpha (i) signalling events
WikiPathways	Monoamine Transport
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 538776	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1261).
Ref 526445	Characteristics of recombinantly expressed rat and human histamine H3 receptors. Eur J Pharmacol. 2002 Oct 18;453(1):33-41.

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Drug Information