Drug Information

Drug General Information
Drug ID
D0P6CN
Former ID
DIB004381
Drug Name
XR-368
Synonyms
Xenovulene; XR-7009
Indication Anxiety disorder [ICD9: 300, 311; ICD10:F32, F40-F42] Terminated [545635]
Company
Xenova Ltd
Canonical SMILES
C12=C(C(=O)[C@@H]3[C@H]1[C@H]([C@H]1[C@](O2)(C/C=C/C(C/<br />C=C(/CC1)\C)(C)C)C)OC3)O
Target and Pathway
Target(s) Gamma-aminobutyric acid receptor Target Info Modulator [534442]
References
Ref 545635Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004007)
Ref 534442Regulation of neuronal and recombinant GABA(A) receptor ion channels by xenovulene A, a natural product isolated from Acremonium strictum. J Pharmacol Exp Ther. 1997 Aug;282(2):513-20.

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