Drug Information

Drug General Information
Drug ID
D0OP7B
Former ID
DIB002106
Drug Name
LY-210073
Drug Type
Small molecular drug
Indication Asthma [ICD10:J45] Terminated [534014]
Company
Eli Lilly & Co
Formula
C30H28O8
Canonical SMILES
c12c(c(=O)c3c(o1)ccc(c3)C(=O)O)ccc(c2CCC(=O)O)OCCCC/C=C<br />/c1ccc(cc1)OC
CAS Number
CAS 148291-65-0
PubChem Compound ID
6450158
Target and Pathway
Target(s) Leukotriene B4 receptor 1 Target Info Modulator [534014]
KEGG Pathway Neuroactive ligand-receptor interaction
NetPath Pathway IL4 Signaling Pathway
Reactome Leukotriene receptors
G alpha (q) signalling events
WikiPathways Nucleotide GPCRs
GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Spinal Cord Injury
GPCR ligand binding
GPCR downstream signaling
References
Ref 534014Design, synthesis, and pharmacological evaluation of potent xanthone dicarboxylic acid leukotriene B4 receptor antagonists. J Med Chem. 1993 Jun 11;36(12):1726-34.
Ref 534014Design, synthesis, and pharmacological evaluation of potent xanthone dicarboxylic acid leukotriene B4 receptor antagonists. J Med Chem. 1993 Jun 11;36(12):1726-34.

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