Drug Information

Drug General Information
Drug ID
D0OC4B
Former ID
DNC011220
Drug Name
7-Hydroxy-4-phenylcoumarin
Drug Type
Small molecular drug
Indication Discovery agent Investigative [531138]
Formula
C15H10O3
Canonical SMILES
C1=CC=C(C=C1)C2=CC(=O)OC3=C2C=CC(=C3)O
InChI
1S/C15H10O3/c16-11-6-7-12-13(10-4-2-1-3-5-10)9-15(17)18-14(12)8-11/h1-9,16H
InChIKey
IVJMJRRORVMRJJ-UHFFFAOYSA-N
PubChem Compound ID
5357479
Target and Pathway
Target(s) Aldose reductase Target Info Inhibitor [531138]
BioCyc Pathway Methylglyoxal degradation III
Acetone degradation I (to methylglyoxal)
KEGG Pathway Pentose and glucuronate interconversions
Fructose and mannose metabolism
Galactose metabolism
Glycerolipid metabolism
Metabolic pathways
NetPath Pathway IL1 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
PathWhiz Pathway Fructose and Mannose Degradation
Pyruvate Metabolism
Pterine Biosynthesis
Glycerolipid Metabolism
Galactose Metabolism
WikiPathways Metapathway biotransformation
Polyol Pathway
Metabolism of steroid hormones and vitamin D
References
Ref 531138Bioorg Med Chem Lett. 2010 Oct 1;20(19):5630-3. Epub 2010 Aug 12.6,7-Dihydroxy-4-phenylcoumarin as inhibitor of aldose reductase 2.
Ref 531138Bioorg Med Chem Lett. 2010 Oct 1;20(19):5630-3. Epub 2010 Aug 12.6,7-Dihydroxy-4-phenylcoumarin as inhibitor of aldose reductase 2.

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