Drug Information

Drug General Information
Drug ID
D0OA8M
Former ID
DIB020923
Drug Name
SC-19220
Synonyms
SC 19220; SC19220
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539224]
Formula
C16H14ClN3O3
InChI
InChI=1S/C16H14ClN3O3/c1-10(21)18-19-16(22)20-9-11-4-2-3-5-14(11)23-15-7-6-12(17)8-13(15)20/h2-8H,9H2,1H3,(H,18,21)(H,19,22)
InChIKey
KNURFLJTOUGOOQ-UHFFFAOYSA-N
PubChem Compound ID
4336830
PubChem Substance ID
6375884, 7980576, 9645084, 11111793, 11113956, 14826747, 17405653, 24278701, 35637713, 46500470, 47944894, 50104757, 50104758, 53778203, 53790367, 57356934, 71739177, 74458452, 85229991, 85231223, 85787597, 90340966, 91722308, 92303261, 103334571, 112856495, 121361980, 124750232, 124799776, 124881429, 124881430, 125334272, 135651018, 135698406, 136351441, 162022781, 162250186, 163137960, 163565051, 178125964, 179150123, 237693855, 241182229, 241375297, 250136930
Target and Pathway
Target(s) Prostaglandin E2 receptor, EP1 subtype Target Info Antagonist [534595]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Pathways in cancer
PANTHER Pathway PI3 kinase pathway
Reactome Prostanoid ligand receptors
G alpha (q) signalling events
WikiPathways Prostaglandin Synthesis and Regulation
GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 539224(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1922).
Ref 534595Molecular cloning and characterization of the four rat prostaglandin E2 prostanoid receptor subtypes. Eur J Pharmacol. 1997 Dec 11;340(2-3):227-41.

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