Drug Information

Drug General Information
Drug ID
D0O9GJ
Former ID
DIB018810
Drug Name
alphabeta-methyleneADP
Synonyms
alpha,beta-methyleneadenosine 5'-diphosphate (alphabetameADP); [alphabetaCH2]ADP
Drug Type
Small molecular drug
Indication Discovery agent Investigative [468154]
Formula
C11H17N5O9P2
InChI
InChI=1S/C11H17N5O9P2/c12-9-6-10(14-2-13-9)16(3-15-6)11-8(18)7(17)5(25-11)1-24-27(22,23)4-26(19,20)21/h2-3,5,7-8,11,17-18H,1,4H2,(H,22,23)(H2,12,13,14)(H2,19,20,21)/t5-,7-,8-,11-/m1/s1
InChIKey
OLCWZBFDIYXLAA-IOSLPCCCSA-N
PubChem Compound ID
92199
PubChem Substance ID
822018, 826841, 837272, 7885577, 7885916, 10225253, 11532930, 15056410, 24896872, 26744166, 26756681, 44423060, 46518245, 50064745, 51091073, 57335171, 76270692, 85149275, 85197808, 85197812, 85756529, 92098536, 103696599, 104406789, 123059313, 128824729, 131349752, 135049476, 136349766, 136349770, 137263091, 139404062, 160644369, 160780821, 162227601, 163124585, 163831629, 178101785, 204356569, 230255671, 241076342, 252319262, 252344743
Target and Pathway
Target(s) 5'-Nucleotidase Target Info Inhibitor [526186]
BioCyc Pathway Purine nucleotides degradation
Urate biosynthesis/inosine 5'-phosphate degradation
Adenosine nucleotides degradation
KEGG Pathway Purine metabolism
Pyrimidine metabolism
Nicotinate and nicotinamide metabolism
Metabolic pathways
PANTHER Pathway Purine metabolism
Pyrimidine Metabolism
Pathway Interaction Database HIF-1-alpha transcription factor network
Reactome Purine catabolism
WikiPathways Differentiation Pathway
miR-targeted genes in muscle cell - TarBase
miR-targeted genes in lymphocytes - TarBase
miR-targeted genes in epithelium - TarBase
Metabolism of nucleotides
References
Ref 468154(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5092).
Ref 5261865'-Nucleotidase from smooth muscle of small intestine and from brain. Inhibition of nucleotides. Biochemistry. 1975 Jun 3;14(11):2362-6.

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