Drug Information

Drug General Information
Drug ID
D0O8RG
Former ID
DNC011283
Drug Name
2-phenyl-N-(1-phenylethyl)quinoline-4-carboxamide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [531249]
Formula
C24H20N2O
Canonical SMILES
CC(C1=CC=CC=C1)NC(=O)C2=CC(=NC3=CC=CC=C32)C4=CC=CC=C4
InChI
1S/C24H20N2O/c1-17(18-10-4-2-5-11-18)25-24(27)21-16-23(19-12-6-3-7-13-19)26-22-15-9-8-14-20(21)22/h2-17H,1H3,(H,25,27)
InChIKey
IEDWYQQEMKCMSQ-UHFFFAOYSA-N
PubChem Compound ID
2849628
Target and Pathway
Target(s) Nigral tachykinin NK(3) receptor Target Info Inhibitor [531249]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Reactome G alpha (q) signalling events
WikiPathways Gastrin-CREB signalling pathway via PKC and MAPK
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 531249J Med Chem. 2010 Nov 25;53(22):8080-8. Epub 2010 Nov 3.Virtual screening to identify novel antagonists for the G protein-coupled NK3 receptor.
Ref 531249J Med Chem. 2010 Nov 25;53(22):8080-8. Epub 2010 Nov 3.Virtual screening to identify novel antagonists for the G protein-coupled NK3 receptor.

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