Drug Information

Drug General Information
Drug ID
D0O5GK
Former ID
DNCL001979
Drug Name
R-phenserine
Synonyms
Posiphen (TN)
Indication Alzheimer disease; Mild cognitive impairment [ICD9: 331.0, 331.83; ICD10:F06.7, G30, G31.84] Phase 2 [548049]
Company
QR Pharma
Target and Pathway
Target(s) Acetylcholinesterase Target Info Inhibitor [527603]
KEGG Pathway Glycerophospholipid metabolism
Cholinergic synapse
PANTHER Pathway Muscarinic acetylcholine receptor 1 and 3 signaling pathway
Muscarinic acetylcholine receptor 2 and 4 signaling pathway
Nicotinic acetylcholine receptor signaling pathway
Pathway Interaction Database ATF-2 transcription factor network
PathWhiz Pathway Phospholipid Biosynthesis
WikiPathways Monoamine Transport
Biogenic Amine Synthesis
Acetylcholine Synthesis
Integrated Pancreatic Cancer Pathway
References
Ref 548049Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800021506)
Ref 527603An overview of phenserine tartrate, a novel acetylcholinesterase inhibitor for the treatment of Alzheimer's disease. Curr Alzheimer Res. 2005 Jul;2(3):281-90.

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