Drug Information

Drug General Information
Drug ID
D0O2AV
Former ID
DIB020422
Drug Name
MRS1486
Synonyms
MRS-1486
Drug Type
Small molecular drug
Indication Discovery agent Investigative [467961]
Formula
C22H27NO3S
InChI
InChI=1S/C22H27NO3S/c1-5-12-17-18(22(25)27-8-4)16(6-2)19(21(24)26-7-3)20(23-17)15-13-10-9-11-14-15/h9-11,13-14H,5-8,12H2,1-4H3
InChIKey
GSMBGLUYORHXJR-UHFFFAOYSA-N
PubChem Compound ID
9843120
PubChem Substance ID
14804918, 24140929, 44941193, 77327645, 85224461, 103329583, 104073743, 127999682, 135650650, 137035279, 232161204
Target and Pathway
Target(s) Adenosine A3 receptor Target Info Antagonist [534684]
Reactome Adenosine P1 receptors
G alpha (i) signalling events
WikiPathways Nucleotide GPCRs
GPCRs, Class A Rhodopsin-like
GPCRs, Other
References
Ref 467961(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 472).
Ref 534684Structure-activity relationships and molecular modeling of 3, 5-diacyl-2,4-dialkylpyridine derivatives as selective A3 adenosine receptor antagonists. J Med Chem. 1998 Aug 13;41(17):3186-201.

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