Drug Information

Drug General Information
Drug ID
D0NM7S
Former ID
DIB018730
Drug Name
A-935142
Synonyms
A935142; A 935142
Drug Type
Small molecular drug
Indication Discovery agent Investigative [542639]
Formula
C18H19F3N2O2
InChI
InChI=1S/C18H19F3N2O2/c19-18(20,21)16-10-15(22-23-16)14-7-5-13(6-8-14)12-3-1-11(2-4-12)9-17(24)25/h5-8,10-12H,1-4,9H2,(H,22,23)(H,24,25)/t11-,12-
InChIKey
YPHFQSYEKIEMNC-HAQNSBGRSA-N
PubChem Compound ID
25125452
PubChem Substance ID
56449703, 223365996, 224195230, 230411145, 239783272, 243674630, 248228027
Target and Pathway
Target(s) Potassium voltage-gated channel subfamily H member 2 Target Info Activator [530115]
PathWhiz Pathway Muscle/Heart Contraction
Reactome Voltage gated Potassium channels
WikiPathways SIDS Susceptibility Pathways
Hematopoietic Stem Cell Differentiation
Potassium Channels
References
Ref 542639(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7661).
Ref 530115Electrophysiologic characterization of a novel hERG channel activator. Biochem Pharmacol. 2009 Apr 15;77(8):1383-90.

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