Drug Information

Drug General Information
Drug ID
D0NF7S
Former ID
DIB012032
Drug Name
R-59494
Drug Type
Small molecular drug
Indication Ischemia [ICD9: 459.89; ICD10:I99.8] Terminated [545149]
Company
Janssen Pharmaceutica NV
Formula
C22H23N3OS
Canonical SMILES
c1(nc2c(s1)cccc2)N(C1CN(CC1)CCCCOc1ccccc1)C
CAS Number
CAS 104588-44-5
PubChem Compound ID
132007
Target and Pathway
Target(s) Sodium channel Target Info Modulator [526753]
KEGG Pathway Dopaminergic synapse
Reactome Interaction between L1 and Ankyrins
References
Ref 545149Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002300)
Ref 526753Veratridine activates a silent sodium channel in rat isolated aorta. Eur J Pharmacol. 1992 Aug 25;219(2):253-9.

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